by Yu An | Jul 10, 2020 | News
OGT suppresses S6K1-mediated macrophage inflammation and metabolic disturbance Enhanced inflammation is believed to contribute to overnutrition-induced metabolic disturbance. Nutrient flux has also been shown to be essential for immune cell activation. Here, we report...
by Qiong Wang | Jun 26, 2020 | News
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids SARS-CoV-2 has caused the COVID-19 pandemic. There is an urgent need for physiological models to study SARS-CoV-2 infection using human...
by Qiong Wang | Jun 22, 2020 | News
Follow In the 2020 CADA Virtual Meeting, the CADA Secretary Dr. Yi Tan presented this year’s CADA Achievement Award to Dr. Liangyou Rui, in recognition of his scientific achievements and contributions to CADA. Dr. Rui is the Louis G. D’Alecy Collegiate...
by Qiong Wang | Jun 17, 2020 | News
Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction Skeletal muscle depends on the precise orchestration of contractile and metabolic gene expression programs to direct fiber type specification and to ensure muscle...
by Qiong Wang | Jun 17, 2020 | News
Follow The ADA Outstanding Scientific Achievement Award (OSAA) is to recognize outstanding scientific achievement by a scientist less than 50 years of age in diabetes research that demonstrates independence of thought, originality, significance of discovery, and...
by Qiong Wang | Jun 16, 2020 | News
Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2 Lysosomal cholesterol egress requires two proteins, NPC1 and NPC2, whose defects are responsible for Niemann-Pick disease type C (NPC). Here, we present systematic structural...
